Medicine

Progressing ASO treatments from development to execution

.Completing enthusiasms.R.S., M.S., H.G. as well as A.A.R. are organizers of the 1M1M campaign. H.G. and also A.A.R. are actually board of supervisors members and also R.S., M.S. and A.A.R. are actually members of the scientific consultatory committee of N1C. A.A.R. reveals employment through LUMC, which possesses licenses on exon-skipping modern technology, some of which has been actually licensed to BioMarin and also subsequently sublicensed to Sarepta. As co-inventor of some of these licenses, A.A.R. was entitled to a reveal of aristocracies. A.A.R. even further discloses working as professional for PTC Rehabs, Sarepta Therapies, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. Previously 5 years, A.A.R. additionally executed impromptu seeking advice from for Alpha Anomeric. A.A.R. additionally discloses subscription of the clinical boards of advisers of Eisai, Hybridize Therapies, Muteness Therapeutics, Sarepta Therapies, Sapreme and also Mitorx. Over the last 5 years, A.A.R. was also a medical advisory board member for ProQR. Pay for A.A.R. u00e2 s consulting as well as advising tasks is actually paid to LUMC. Previously 5 years, LUMC also got sound speaker gratuity coming from PTC Rehabs, Alnylam Netherlands, Italfarmaco as well as Pfizer and financing for agreement research study from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Project funding is obtained coming from Sarepta Therapeutics and also Entrada by means of unregulated grants. H.G. possesses absolutely nothing to make known in regard to the subjects dealt with within this composition. In the past 5 years, he has also acquired consultancy gratuity coming from UCB. M.S. obtained consultancy gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and also Solaxa over the last 5 years, all irrelevant to the present manuscript. R.S. possesses nothing to reveal in relation to the subject matters covered in this particular composition. She has actually acquired audio speaker and/or working as a consultant gratuity or even financing contributions from Abbvie, Bial, STADA as well as Everpharma before 5 years.